MTHFR results

Finally got my 23andMe results and ran them through GeneticGenie.  Turns out I am Heterozygous MTHFR A1298C.  There is speculation that this can cause up to a 30% reduction in enzymatic function.  I don't know that there is any solid proof with this particular SNP (Single Nucleotide Polymorphisms), pronounced "snip"*.  There is also concern that it may impact neurotransmitter formation (seratonin, dopamine, epinephrine, norepinephrine, melatonin). One of the possible symptoms - IBS.  With a heterozygous SNP the effect is far less than if the SNP was homozygous (meaning you got an altered gene from both parents instead of just one). There can also be combinations of SNPs that have a far greater impact. For more information you can check out the following website and podcasts:

http://mthfr.net/ - Dr. Ben Lynch's website

http://www.blogtalkradio.com/undergroundwellness/2014/11/19/dr-ben-lynch-mthfr-made-easy - You can never go wrong with a Sean Croxton interview!

Testing is easy.  You order a 23andMe kit ($99).  Once you get the results back, you can upload them into Genetic Genie (requested donation of $10) and they spit back a report in a matter of seconds.  Of course once you get these results back it's best to check with your healthcare provider to see what steps need to be taken to support your body.  I will do that in a couple of weeks and let you know what Dr. Keller recommends.

*From GeneticGenie "We have two copies of most of the genes we are born with - one from our mother and one from our father. Genetic Genie uses the SNPs (Single Nucleotide Polymorphisms) generated from your unique DNA sequence to determine if one or both copies of your genes have a mutation at a specific location in a specific gene."