Monday, April 13, 2015

More than you ever wanted to know about biofilms...

I am not a fast reader, if I want to absorb anything that is.  This article about biofilms is long and kind of scary but worth the read.  Take this exerpt:

"In just a few short years, the potential of biofilms to cause debilitating chronic infections has become so clear that there is little doubt that biofilms are part of the pathogenic mix or “pea soup” that cause most or all chronic “autoimmune” and inflammatory diseases."

And in most cases these bacterial infections won't kill you, at least not quicky, they are just debilitating.  The bacteria don't want to kill the host (you) because then they would have no place to live.

I've been consistently taking some sort of antimicrobial for over a year.  After reading this I may take a break and then start up again.

"But in the case of low, pulsed dosing, where an antibiotic is administered, withdrawn, then administered again, the first application of antibiotic will eradicate the bulk of biofilm cells, leaving persister cells behind. Withdrawl of the antibiotic allows the persister population to start growing. Since administration of the antibiotic is temporarily stopped, the survival of persisters is not enhanced. This causes the persister cells to lose their phenotype (their shape and biochemical properties), meaning that they are unable to switch back into biofilm mode. A second application of the antibiotic should then completely eliminate the persister cells, which are still in planktonic mode."

After reading this I'm not sure I'll be able to eat anything raw that is store bought or from a restaurant, the proposition is just too laden with risk.  That may sound extreme, but it's taken a long time for me to get this well, a nasty bout of foodborne illness could put me back to square one or further back even!

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